All dogs shed cells from their bladder and urinary tract each time they pass urine. CADET® BRAF detects the presence of cells in the urine that contain mutated copies of the dog BRAF gene. Detection of the BRAF mutation is indicative that the dog has a TCC/UC.
CADET® BRAF offers a forensic level of detection, so sensitive that it can detect TCC/UC with as few as ten mutant-bearing cells in the urine sample. Combined with a specially formulated urine preservation agent and optimized DNA extraction process, CADET® BRAF can detect the presence of TCC/UC several months before any clinical signs of disease are present.